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. 2023 Nov 23;8(48):45502–45509. doi: 10.1021/acsomega.3c05488

Table 1. In Vitro Cytotoxicity of the Synthesized Noscapine and Cotarnine Analogues.

IC50 (μM) compound IC50a (μM) compound
902.1 10a 181.6 6a
144.6 10b 200.5 6b
489.7 10c 145.5 6c
708.4 10d 168.2 6d
541.2 10e 268.4 6e
659.2 10f 360 6f
657.5 10g 101.4 6g
268.1 10h 11.2 6h
54.5 10i 16.3 6i
96.3 10j 100.8 6j
575.3 cotarnine 215.5 noscapine
a

IC50: half-maximal inhibitory concentration.