Table 1. In Vitro Cytotoxicity of the Synthesized Noscapine and Cotarnine Analogues.
| IC50 (μM) | compound | IC50a (μM) | compound |
|---|---|---|---|
| 902.1 | 10a | 181.6 | 6a |
| 144.6 | 10b | 200.5 | 6b |
| 489.7 | 10c | 145.5 | 6c |
| 708.4 | 10d | 168.2 | 6d |
| 541.2 | 10e | 268.4 | 6e |
| 659.2 | 10f | 360 | 6f |
| 657.5 | 10g | 101.4 | 6g |
| 268.1 | 10h | 11.2 | 6h |
| 54.5 | 10i | 16.3 | 6i |
| 96.3 | 10j | 100.8 | 6j |
| 575.3 | cotarnine | 215.5 | noscapine |
IC50: half-maximal inhibitory concentration.