Table 3. Mixture Associations Using BWQS Regression Modelsa.
Hormones | Second trimester | Third trimester |
---|---|---|
PC (95% CrI) | PC (95% CrI) | |
∑Cortisol | –2.33 (−18.3, 16.2) | 5.74 (−9.89, 23.5) |
∑Cortisone | 0.06 (−14.0, 16.7) | 11.0 (−4.28, 27.3) |
11-dehydrocorticosterone | –0.39 (−22.2, 27.5) | 5.55 (−17.2, 32.9) |
Testosterone | –4.50 (−22.3, 17.5) | 17.0 (−3.63, 41.6) |
Progesterone | 4.64 (−12.9, 26.9) | 10.3 (−7.36, 30.2) |
CC Ratio | –3.22 (−13.4, 7.68) | –5.50 (−13.6, 3.44) |
TC Ratio | –3.15 (−23.5, 23.3) | 10.3 (−10.3, 35.9) |
Note: Percent change (PC) in hormone levels per quartile increase of the phthalate mixture, with its related 95% Credible Interval (95% CrI). The weight contributed by each chemical compound to the most relevant mixture associations can be consulted in Figure S8. Mixture models were adjusted for the same set of covariates included in single-pollutant models. Abbreviations: CC (cortisol to cortisone); TC (testosterone to cortisol).