Table 3.
Correlations between the performance in the Morris water maze test and the hippocampal mRNA levels of SIRT1, BDNF, PSD-95, and SYP [r (p)].
| Tasks | Indexes | Groups | mRNA levels | |||
|---|---|---|---|---|---|---|
| SIRT1 | BDNF | PSD-95 | SYP | |||
| Morris water maze test | Escape latency | Control+saline | −0.454 (0.259) | −0.515 (0.191) | −0.342 (0.407) | −0.592 (0.122) |
| Control+Res | −0.884 (0.004)** | −0.918 (0.001)** | −0.918 (0.001)** | −0.933 (0.001)** | ||
| MLPS+saline | −0.892 (0.003)** | −0.855 (0.007)** | −0.881 (0.004)** | −0.900 (0.002)** | ||
| MLPS+Res | −0.939 (0.001)** | −0.908 (0.002)** | −0.938 (0.001)** | −0.891 (0.003)** | ||
| Distance swam | Control+saline | −0.589 (0.125) | −0.676 (0.066) | −0.511 (0.195) | −0.754 (0.031)* | |
| Control+Res | −0.862 (0.006)** | −0.866 (0.005)** | −0.749 (0.033)* | −0.808 (0.015)* | ||
| MLPS+saline | −0.861 (0.006)** | −0.854 (0.007)** | −0.851 (0.007)** | −0.916 (0.001)** | ||
| MLPS+Res | −0.862 (0.006)** | −0.823 (0.012)* | −0.802 (0.017)* | −0.893 (0.003)** | ||
| Percentage of time swam | Control+saline | 0.550 (0.158) | 0.687 (0.060) | 0.435 (0.282) | 0.769 (0.026)* | |
| Control+Res | 0.892 (0.003)** | 0.929 (0.001)** | 0.951 (0.000)** | 0.947 (0.000)** | ||
| MLPS+saline | 0.972 (0.000)** | 0.904 (0.002)** | 0.989 (0.000)** | 0.966 (0.000)** | ||
| MLPS+Res | 0.871 (0.005)** | 0.966 (0.000)** | 0.939 (0.001)** | 0.852 (0.007)** | ||
| Percentage of distance swam | Control+saline | 0.102 (0.809) | 0.666 (0.071) | 0.091 (0.831) | 0.441 (0.274) | |
| Control+Res | 0.819 (0.013)* | 0.845 (0.008)** | 0.846 (0.008)** | 0.853 (0.007)** | ||
| MLPS+saline | 0.877 (0.004)** | 0.730 (0.040)* | 0.932 (0.001)** | 0.874 (0.005)** | ||
| MLPS+Res | 0.804 (0.016)* | 0.865 (0.006)** | 0.935 (0.001)** | 0.830 (0.011)* | ||
Res, resveratrol; MLPS, maternal lipopolysaccharide (LPS) exposure. *p < 0.05; **p < 0.01.