Figure 4. Cellular fitness of yeast with disrupted Cse4^END binding.

• A
  Growth of cse4 mutants. Loss of a complementing CSE4 plasmid (pRS316‐CSE4) was induced by growth on 5‐FOA. Test cse4 alleles are indicated at left (cse4‐1A – L41A; cse4‐2A – L41,42A).
• B–D
  Haploid progeny from sporulation of the indicated heterozygous diploid strain (left). Spore genotypes and mutant alleles are given at right. Meiotic products from each tetrad are arranged vertically.

Source data are available online for this figure.