Table 2.
In vitro PK/PD relationship results of micafungin against C. albicans isolates for CLSI and EUCAST in the presence and absence of 10% human pooled serum
Conditions | Method | Mean (95%CI) fAUC0–24/MIC: | |
---|---|---|---|
Stasis | 1-log kill | ||
10% human pooled serum | CLSI | 2.8 | 9.2 |
(1.8–4.6) | (5.2–18.7) | ||
EUCAST | 2.8 | 7.9 | |
(1.6–4.8) | (4.3–17.5) | ||
without 10% human pooled serum | CLSI | 36 | 57 |
(23–67) | (34–121) | ||
EUCAST | 38 | 58 | |
(26–64) | (37–113) |