Table 2.
Univariate analysis: comparison of Single-ICD and Multiple-ICD groups.
| Single-ICD group (n = 21) | Multiple-ICD group (n = 12) | ||
|---|---|---|---|
| Demographics characteristics | |||
| Gender (Male) | 11 (52.38%) | 7 (58.33%) | 0.741 |
| History of coffee (Yes) | 0 (0.00%) | 2 (16.67%) | 0.054 |
| History of smoking (Yes) | 4 (19.05%) | 1 (8.33%) | 0.409 |
| History of alcohol (Yes) | 4 (19.05%) | 2 (16.67%) | 0.865 |
| Age (years) | 66.0 (59.0,68.5) |
65.5 (55.0,72.3) |
0.94 |
| Education level (years) | 0.791 | ||
| 0 ~ 6 | 3 (14.29%) | 2 (18.18%) | |
| 7 ~ 9 | 8 (38.10%) | 5 (45.45%) | |
| 10 ~ 12 | 4 (19.05%) | 2 (18.18%) | |
| >12 | 6 (18.57%) | 3 (17.17%) | |
| Disease duration (years) | 9.0 (3.0,12.0) |
6.0 (4.3,11.5) |
0.523 |
| Motor symptoms | |||
| UPDRS III | 64.0 (42.5,73.0) |
52.5 (38.0,87.0) |
0.837 |
| H-Y grading | 0.545 | ||
| 1 | 1 (4.76%) | 2 (18.18%) | |
| 1.5 | 1 (4.76%) | 1 (9.09%) | |
| 2 | 9 (42.56%) | 4 (36.36%) | |
| 2.5 | 1 (4.76%) | 0 (0%) | |
| 3 | 9 (42.56%) | 5 (45.45%) | |
| 4 | 0 (0%) | 0 (0%) | |
| 5 | 0 (0%) | 0 (0%) | |
| Dyskinesia (Presence) | 6 (28.57%) | 2 (16.67%) | 0.443 |
| Non-motor symptoms | |||
| HAMD (scores ≥21) | 11 (52.38%) | 3 (25.00%) | 0.126 |
| HAMA (scores ≥14) | 15 (71.43%) | 6 (50.00%) | 0.218 |
| AES (scores ≥14) | 15 (71.43%) | 11 (91.67%) | 0.171 |
| RBDSQ (scores ≥5) | 15 (71.43%) | 6 (50.00%) | 0.218 |
| MoCA | 22.0 (17.5,24.0) |
22.0 (15.5,24.0) |
0.895 |
| MMSE | 27.0 (24.0,28.5) |
27.5 (26.3,28.8) |
0.677 |
| Medication | |||
| LEDD | 500.0 (412.5,793.8) |
400.0 (300.0,875.0) |
0.293 |
| Dopamine receptor agonists (Yes) | 15 (71.43%) | 7 (58.33%) | 0.443 |
| Pramipexole (Yes) | 10 (47.62%) | 6 (50.00%) | 0.895 |
| Amantadine (Yes) | 8 (38.10%) | 1 (8.33%) | 0.065 |
| Selegiline (Yes) | 1 (4.76%) | 1 (8.33%) | 0.679 |
Probability presented for qualitative variables. Median and interquartile range for quantitative variables. *p < 0.05.