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. 2023 Nov 21;14:1288223. doi: 10.3389/fimmu.2023.1288223

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Copyright © 2023 Kong, Yang, Ding, Cheng and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heat map of immune marker expression in rainbow trout. (A) The heat map illustrates the quantitative qPCR results of relative mRNA levels for the selected immune markers in F. columnare-infected fish versus control fish measured at 0.5, 1, 4, 7, 14, 21, and 28 days post-infection (n = 6 fish per group) in the ocular mucosa of rainbow trout. (B) Heat map in the head kidney. (C) Heat map in the spleen. The color value represents fold change. Data are expressed as mean fold increase in expression. The color represents the relative expression of the corresponding genus, with red indicating the higher expression and green indicating the lower expression.