Table 10.

Sensitivity, specificity, and Youden’s index for various operationalization of self-and informant-reported SCC in Petersen MCI at baseline for dementia after 2 to 7 years of follow-up.

Follow-up year (# of participants)	SCC definition	Sensitivity	Specificity	Youden’s index
2 (501)	Petersen with no SCC	0.829	0.560	0.389
	Petersen + any self-reported SCC	0.793	0.605	0.398
	Petersen + high avg. self-reported SCC	0.524	0.813	0.337
	Petersen + any informant-reported SCC	0.588	0.751	0.339
	Petersen + high avg. informant-reported SCC	0.505	0.870	0.375
3 (382)	Petersen with no SCC	0.825	0.572	0.397
	Petersen + any self-reported SCC	0.789	0.617	0.406
	Petersen + high avg. self-reported SCC	0.516	0.823	0.339
	Petersen + any informant-reported SCC	0.582	0.761	0.342
	Petersen + high avg. informant-reported SCC	0.492	0.881	0.374
5 (244)	Petersen with no SCC	0.820	0.590	0.410
	Petersen + any self-reported SCC	0.783	0.636	0.418
	Petersen + high avg. self-reported SCC	0.504	0.837	0.341
	Petersen + any informant-reported SCC	0.572	0.776	0.348
	Petersen + high avg. informant-reported SCC	0.473	0.897	0.371
7 (145)	Petersen with no SCC	0.813	0.613	0.426
	Petersen + any self-reported SCC	0.775	0.658	0.433
	Petersen + high avg. self-reported SCC	0.490	0.853	0.343
	Petersen + any informant-reported SCC	0.560	0.794	0.353
	Petersen + high avg. informant-reported SCC	0.452	0.914	0.366