Table 9.
Sensitivity, specificity, and Youden’s index for various operationalization of self- and informant-reported SCC in Jak/Bondi MCI at baseline for dementia after 2 to 7 years of follow-up.
| Follow-up year (# of participants) | SCC definition | Sensitivity | Specificity | Youden’s index |
|---|---|---|---|---|
| 2 (501) | Jak/Bondi with no SCC | 0.746 | 0.675 | 0.421 |
| Jak/Bondi + any self-reported SCC | 0.734 | 0.694 | 0.429 | |
| Jak/Bondi + high avg. self-reported SCC | 0.514 | 0.863 | 0.377 | |
| Jak/Bondi + any informant-reported SCC | 0.528 | 0.822 | 0.350 | |
| Jak/Bondi + high avg. informant-reported SCC | 0.497 | 0.902 | 0.399 | |
| 3 (382) | Jak/Bondi with no SCC | 0.740 | 0.688 | 0.428 |
| Jak/Bondi + any self-reported SCC | 0.728 | 0.708 | 0.436 | |
| Jak/Bondi + high avg. self-reported SCC | 0.502 | 0.874 | 0.376 | |
| Jak/Bondi + any informant-reported SCC | 0.519 | 0.832 | 0.352 | |
| Jak/Bondi + high avg. informant-reported SCC | 0.480 | 0.914 | 0.394 | |
| 5 (244) | Jak/Bondi with no SCC | 0.731 | 0.708 | 0.440 |
| Jak/Bondi + any self-reported SCC | 0.718 | 0.728 | 0.447 | |
| Jak/Bondi + high avg. self-reported SCC | 0.483 | 0.891 | 0.374 | |
| Jak/Bondi + any informant-reported SCC | 0.505 | 0.848 | 0.353 | |
| Jak/Bondi + high avg. informant-reported SCC | 0.452 | 0.931 | 0.383 | |
| 7 (145) | Jak/Bondi with no SCC | 0.720 | 0.732 | 0.453 |
| Jak/Bondi + any self-reported SCC | 0.706 | 0.753 | 0.459 | |
| Jak/Bondi + high avg. self-reported SCC | 0.462 | 0.908 | 0.370 | |
| Jak/Bondi + any informant-reported SCC | 0.488 | 0.866 | 0.355 | |
| Jak/Bondi + high avg. informant-reported SCC | 0.421 | 0.948 | 0.369 |