TABLE 5.
The 3D and 2D binding interactions showed that all proposed molecules interacted with a higher number of residues via hydrophobic interactions than Foretinib and compound 22.
| Complex | 3D binding interactions | 2D binding interactions |
|---|---|---|
| Foretinib-VEGFR-2 |
|
|
| MOL22-VEGFR-2 |
|
|
| T01-VEGFR-2 |
|
|
| T02-VEGFR-2 |
|
|
| T03 –VEGFR-2 |
|
|
| T04- VEGFR-2 |
|
|
| T05- VEGFR-2 |
|
|
| T06- VEGFR-2 |
|
|