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. Author manuscript; available in PMC: 2023 Dec 7.
Published in final edited form as: Anal Chem. 2023 Jun 26;95(27):10211–10220. doi: 10.1021/acs.analchem.3c00462

Figure 4.

Figure 4.

S. mutans and S. aureus can be captured on CandyCollect devices from all the participants who had positive results from spit tube and/or ESwab™ samples. CandyCollect, ESwab™, and SpeciMAX Stabilized Saliva Collection Kits (Spit tube) were sent to 14 research participants for a proof-of-concept test. The concentrations of (A) S. mutans and (B) S. aureus from participants’ saliva, collected over two days by three different methods, were analyzed via qPCR and converted to estimated copy number of bacterial DNA/mL in the original saliva sample (see Methods section “Human subject data analysis” for detailed description of calculations). Each dot represents the average of two qPCR technical duplicates from one sample (three samples were collected for the CandyCollect device and ESwab™, and one for the Spit tube each day). Bar graphs represent the mean ± SEM of n = 3 CandyCollect devices or ESwab™. Participants only completed one spit tube per day.