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. 2023 Nov 21;13:1221352. doi: 10.3389/fonc.2023.1221352

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Copyright © 2023 Tanaka, Enokida, Okano, Fujisawa, Tanaka, Takeshita, Onaga, Hoshi, Wada, Sato, Ueda and Tahara

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Response of patients treated with PE-based chemotherapy following ICI monotherapy. (A) Best response to PE-based chemotherapy by RECIST ver.1.1. (B) Spider plot showing the change in the sum of tumor diameters based on RECIST during PE-based chemotherapy. PCE, paclitaxel+carboplatin+cetuximab; PTX+Cmab, paclitaxel+cetuximab, TTP, time to response. Note: ICI, pembrolizumab or nivolumab monotherapy; PE-based chemotherapy, PCE or PTX+Cmab.