Table 1.
Treatment | Concentration | Dose (1x per day) | Route (OG, IP, SC) | n |
---|---|---|---|---|
Controls | ||||
Infected, untreated (OG Ctrl) | Water | 0.2 mL/mouse | OG | 3 |
Infected, untreated (IP Ctrl) | PBS | 0.2 mL/mouse | IP | 5 |
Infected, untreated (SC Ctrl) | 0.09% Saline +5% DMSO | 0.2 mL/mouse | SC | 2 |
Total | 10 | |||
Therapies | ||||
Azlocillin | 15 mg/mL | 100 mg/kg | IP | 5 |
Bactrim* | 10 mg/mL | 62.5 mg/kg | OG | 5 |
Disulfiram | 20 mg/mL | 100 mg/kg | OG | 5 |
Carbomycin | 25 mg/mL | 200 mg/kg | SC | 5 |
Dapsone | 5 mg/mL | 15 mg/kg | OG | 5 |
Rifampicin | 10 mg/mL | 30 mg/kg | OG | 5 |
Cefotaxime | 25 mg/mL | 100 μg/mouse | IP | 5 |
Loratadine | 5 mg/mL | 20 mg/kg | OG | 5 |
Total | 40 |
OG, oral gavage; IP, intraperitoneal; SC, subcutaneous. *Bactrim = Trimethoprim-Sulfamethoxazole (TMP-SMX) (62.5 mg/kg = TMP component).