Table 4.
Culture results for xenodiagnostic ticks following monotherapy treatment of infected mice.
| Treatments | Cultures of Xenodiagnostic Ticks | |||
|---|---|---|---|---|
| BSK-H^ | mBSK-II^ | Combined Cultures^ | p value | |
| Infected Untreated (OG) | 1/3 | ND | 1/3 | |
| Infected Untreated (IP) | 5/5 | 3/3 | 5/5 | |
| Infected Untreated (SC) | 1/2 | 1/2 | 1/2 | |
| Azlocillin (IP) | 4/5 | ND | 4/5 | 1b |
| Bactrim (OG) | 5/5 | ND | 5/5 | 0.1071a |
| Disulfiram (OG) | 3/5 | ND | 3/5 | 1a |
| Carbomycin (SC) | 4/5 | 4/5 | 4/5 | 0.5238c |
| Dapsone (OG) | 2/5 | 3/5 | 3/5 | 1a |
| Rifampicin (OG) | 2/5 | 2/5 | 2/5 | 1a |
| Cefotaxime (IP) | 1/5 | 1/5 | 1/5 | 0.0476b* |
| Loratadine (OG) | 3/5 | 3/5 | 3/5 | 1a |
ND, Not done; OG, oral gavage; IP, intraperitoneal; SC, subcutaneous. Combined cultures compared to a = OG control group, b = IP control group, c = SC control group. ^ Number of pooled ticks per mouse positive/total number of mice tested. * Statistically significant. Fisher exact test, the result is significant at p < 0.05.