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. 2023 Nov 21;14:1293300. doi: 10.3389/fmicb.2023.1293300

Table 7.

Summary of the test results of the effective treatment groups.

Treatment* Tissues Xeno Ticks
Culture^ PCR 16Sa PCR ospCa Culture^ PCR 16S PCR ospA RT-PCR 16S RT-PCR ospA IFA
Infected Untreated Group + + + + + +
+ + + + + +
+ + + + + + +
+ + + + +
+ + + + + + +
Doxycycline (OG) + Ceftriaxone (IP)
+
+
Doxycycline (OG) + Ceftriaxone (IP) + Carbomycin (SC)
Dapsone (OG) + Rifampicin (OG) N/A N/A N/A N/A
+
Dapsone (OG) + Clofazimine (OG)
+ +
+
Dapsone (OG) + Clofazimine (OG) + Rifampicin (OG)
+
+
Cefotaxime (IP) + Loratadine (OG) + Doxycycline (OG)
Cefotaxime (IP) + Doxycycline (OG)
+
+

*Every row in each group represents one mouse. ^Culture in BSK-H or mBSK-II. N/A = Not available. + = positive. − = negative. a = at least from one tissue and maximum 5 tissues. Tick section represents the pooled ticks tested per mouse except for IFA where the results represent at least one tick positive per mouse.