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. 2023 Nov 22;14:1289460. doi: 10.3389/fneur.2023.1289460

Table 1.

Overall patients’ characteristics.

Age at symptom onset, years, mean (SD) 44.1 (14.5)
Time from symptom onset to diagnosis, months, mean (SD) 53.3 (59.2)
Female, n (%) 154 (75.1)
Race, n (%)
White
Black
Asian
Other

135 (65.9)
51 (24.9)
5 (2.4)
8 (3.9)
Ethnicity, n (%)
Hispanic

10 (4.9)
GAD-65 antibody status
Serum positive, n (%)
Titer IU/mL, mean (SD)
CSF positive, n (% of tested)

175 (86)
171094 (583353)
52 (59.8)
Other SPSD antibody status
Glycine serum positive, n (% of tested)
Amphiphysin serum positive, n (%)

11 (5.4)
7 (3.4)
SPSD phenotype, n (%)
Classic SPS
SPS-plus
Partial SPS
Pure CA
PERM
Possible SPS

135 (66)
36 (18)
8 (4)
6 (3)
12 (6)
8 (4)

SD = standard deviation; GAD-65 = glutamic acid decarboxylase-65; IU/mL, international units/milliliter; SPSD, stiff person spectrum disorder; SPS, stiff person syndrome; CA, cerebellar ataxia; PERM, progressive encephalomyelitis with rigidity and myoclonus.