Table 1.
Overall patients’ characteristics.
| Age at symptom onset, years, mean (SD) | 44.1 (14.5) |
|---|---|
| Time from symptom onset to diagnosis, months, mean (SD) | 53.3 (59.2) |
| Female, n (%) | 154 (75.1) |
|
Race, n (%) White Black Asian Other |
135 (65.9) 51 (24.9) 5 (2.4) 8 (3.9) |
|
Ethnicity, n (%) Hispanic |
10 (4.9) |
|
GAD-65 antibody status Serum positive, n (%) Titer IU/mL, mean (SD) CSF positive, n (% of tested) |
175 (86) 171094 (583353) 52 (59.8) |
|
Other SPSD antibody status Glycine serum positive, n (% of tested) Amphiphysin serum positive, n (%) |
11 (5.4) 7 (3.4) |
|
SPSD phenotype, n (%) Classic SPS SPS-plus Partial SPS Pure CA PERM Possible SPS |
135 (66) 36 (18) 8 (4) 6 (3) 12 (6) 8 (4) |
SD = standard deviation; GAD-65 = glutamic acid decarboxylase-65; IU/mL, international units/milliliter; SPSD, stiff person spectrum disorder; SPS, stiff person syndrome; CA, cerebellar ataxia; PERM, progressive encephalomyelitis with rigidity and myoclonus.