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. 2023 Nov 21;14:1269605. doi: 10.3389/fphar.2023.1269605

TABLE 10.

Presence of acne in the participants in the two groups, berberine (B) and control (C), at enrolment and after 90 days of treatment.

Presence of acne B–baseline (n = 51) C–baseline B–90 days C–90 days
Number of subjects, n 51 55 51 55
Yes, n (%) 29 (56.9%) 28 (50.9%) 13 (25.5%) 19 (34.5%)
Mild, n (%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 1 (1.80%)
No, n (%) 22 (43.1%) 27 (49.1%) 26 (51.0%) 30 (54.5%)
Improved, n (%) 0 (0.0%) 0 (0.0%) 12 (23.5%) 5 (9.1%)
p between “baseline” values: 0.5389 between “90 days” values: p < 0.05

The detailed acne data of all participants are available in Supplementary Material S6. For detailed statistics (Likelihood Ratio, Pearson, and Fisher) see Supplementary Material S7.