TABLE 4.
Metabolic descriptive statistics, expressed as mean ± standard error, of participants in the two groups, berberine (B; n = 51) and control (C; n = 55), at enrolment and after 90 days of treatment.
| Group/Parameter | Baseline | After 90 days | p* |
|---|---|---|---|
| B/Fasting glucose (mg/dL) | 86.24 ± 2.42 | 85.62 ± 2.42 | n. s |
| C/Fasting glucose (mg/dL) | 90.03 ± 2.32 | 88.91 ± 2.32 | n. s |
| B/Fasting insulin (µUI/mL) | 36.99 ± 5.89 | 36.77 ± 5.91 | n. s |
| C/Fasting insulin (µUI/mL) | 39.78 ± 5.77 | 36.14 ± 5.67 | n. s |
| B/Hb A1C (%) | 5.25 ± 0.15 | 5.12 ± 015 | n. s |
| C/Hb A1C (%) | 5.45 ± 0.15 | 5.22 ± 0.15 | n. s |
| B/TC (mg/dL) | 166.44 ± 6.32 | 155.41 ± 6.32 | 0.0192 |
| C/TC (mg/dL) | 180.68 ± 5.66 | 166.14 ± 5.66 | 0.0019 |
| B/TG (mg/dL) | 136.73 ± 11.03 | 118.23 ± 11.11 | n. s |
| C/TG (mg/dL) | 145.91 ± 10.62 | 119.15 ± 10.62 | 0.0433 |
| B/HDL (mg/dL) | 44.41 ± 1.82 | 43.97 ± 1.84 | n. s |
| C/HDL (mg/dL) | 41.69 ± 1.75 | 43.95 ± 1.75 | n. s |
| B/LDL (mg/dL) | 111.14 ± 4.37 | 104.80 ± 4.39 | n. s |
| C/LDL (mg/dL) | 113.99 ± 4.31 | 105.76 ± 4.21 | n. s |
Statistics calculated as a comparison between “baseline” and between “after 90 days” values demonstrated not significant differences. *statistics calculated as “after 90 days” versus “baseline”. Hb A1C, glycated haemoglobin; TC, total cholesterol; TG, triglycerides; HDL, high density lipoprotein; LDL, low density lipoprotein; n. s., not significant.