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. 2023 Nov 21;14:1269605. doi: 10.3389/fphar.2023.1269605

TABLE 5.

Liver Enzymes and CRP descriptive statistics, expressed as mean ± standard error, of participants in the two groups, berberine (B; n = 51) and control (C; n = 55), at enrolment and after 90 days of treatment.

Group/Parameter Baseline After 90 days p*
B/AST (U/L) 25.22 ± 2.64 24.85 ± 2.64 n. s
C/AST (U/L) 24.91 ± 2.52 28.04 ± 2.52 n. s
B/ALT (U/L) 32.11 ± 3.55 30.09 ± 3.55 n. s
C/ALT (U/L) 36.78 ± 3.32 39.82 ± 3.32 n. s
B/Bilirubin (mg/dL) 0.60 ± 0.03 0.52 ± 0.03 n. s
C/Bilirubin (mg/dL) 0.56 ± 0.03 0.56 ± 0.03 n. s
B/ALP (U/L) 129.82 ± 11.45 118.85 ± 11.45 n. s
C/ALP (U/L) 124.51 ± 11.03 137.67 ± 11.03 n. s
B/γ-GT (U/L) 24.95 ± 2.37 20.31 ± 2.37 n. s
C/γ-GT (U/L) 20.58 ± 2.29 24.37 ± 2.29 n. s
B/CRP (U/L) 2.29 ± 0.47 2.01 ± 0.47 n. s
C/CRP (U/L) 2.30 ± 0.45 2.69 ± 0.45 n. s

Statistics calculated as a comparison between “baseline” and between “after 90 days” values demonstrated not significant differences. *statistics calculated as “after 90 days” versus “baseline. AST, alanine aminotransferases; AST, aspartate aminotransferases; ALP, alkaline phosphatase; γ-GT, γ -Glutamyl Transferase; CRP, C Reactive Protein; n. s., not significant.