Supplemental Table1. P-value threshold and related parameters on PRS construction .

Traits	P-threshold	Number of SNP	R2
HbA1c	5.0 × 10-8	102	0.0083587720365206
	0.001	1523	0.0069292604848436
	0.01	5760	0.0061782942260876
	0.05	16637	0.0108040782866358
	0.1	26742	0.0111353862108406
	0.2	42845	0.0111962866537727
	0.3	56383	0.0102524876262533
	0.4	68077	0.0101184426932776
	0.5	78302	0.0092796911886064

Bold fonts in this table indicate the best fit and settings for our analysis. PRS, polygenic risk score.