Fig. 1.

Single-cell RNA sequencing showing cell profiles in DM mouse hearts. (A) Workflow for single-cell RNA transcriptome experiments. (B) t-SNE plot showing distinction of overall cell profiles between Ctrl (n = 4, shown in red) and DM (n = 4, shown in blue) groups. (C-D) t-SNE showing 20 cell clusters (C) and 12 cell types (D) in the integrated single-cell transcriptomes acquired from the Ctrl and DM groups. (E) Bar graph representing the frequency of cells acquired in each cluster. (F) Dot plot showing cell-specific markers. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)