Myocardial infarction (MI) is a leading cause of death globally.

Hydrogels have low toxicity and are highly stable, with good biocompatibility, biodegradability, and transformability, moderate mechanical properties, and proper elasticity, making hydrogels promising biomaterials in treating MI.

Hydrogels can be divided into natural and synthetic types.

Hydrogels have different cross-linking methods.

Hydrogels can be delivered to the heart by multiple routes.

Hydrogels can be used as carriers for delivering drugs, stem cells, small molecules, and other treatments for MI.