Table 1.

Patient and tumor characteristics.

Patient	No 1	No 2	No 3	No 4	No 5	No 6
Primary tu/ relapse	Primary	Primary	Primary	Primary	Relapse	Primary
Age at dg	30 months	5 months	30 months	21 months	29 months	13 years
Localization of tumor	Brain–supratentorial, M0	Brain–supratentorial, M0	Brain–infratentorial, M0	Brain–infratentorial, M0	Metastatic relapse spinal cord	Right ovary
Sex	Female	Male	Male	Female	Male	Female
Histology	AT/RT	AT/RT	AT/RT	AT/RT	AT/RT	Rhabdoid tumor
Subtype	SHH	SHH	SHH	Not known	Not known	Not applicable
Somatic alteration	SMARCB1 c.157C>T/p.R53* + LOH	SMARCB1 deletion	SMARCB1 c.618G>A/p.W206* + SMARCB1 loss	SMARCB1 deletion	SMARCB1 loss	SMARCA4 loss
Germline alteration	No	No	No	No	SMARCB1 c.1005del/p.Y335*	SMARCA4 c.260del/p.D87fs