Table 3.

A summary of the pathology detection patterns of aSyn non-modified and PTM antibodies on LBD substantia nigra.

Antibody	Neuronal				Glial		Extrasomal
	LBs	Diffuse cytoplasmic with an aggregate	Punctate cytoplasmic	LNs & neuropil dots	Astroglial	Coiled body-like oligodendroglial
LASH-EGTNter 1–20	++	++	–	++	–	+	+
LASH-BL 34–45	+++	+	+++	+++	+++	+	+
LASH-BL 80–96	++	+	++	++	++	+	+
BD SYN-1 91–99	++	+	++	++	++	+	+
2F10-E12 110–115	+++	++	–	+++	–	++	+
AB 134–138	++	++	–	++	–	–	+
LASH-BL pY39	+	–	–/+	+	+	+	+
LASH pS87	+	+	–/+	+	–	–	+
AB pY125	–	+	–/+	–	–	–	–
AB EP1536Y pS129	+++	++	–	+++	–	+	+
AB pY133	+	+	–	+	–	–	+
AB pY136	++	–	–	++	–	–	+
LASH-EGT nY39	+	+	++	+	++	–	++
6A3-E9 aSyn-120	–	+	–	–	–	–	++

− absent, + mild, ++ moderate, +++ frequent, aSyn alpha-synuclein, LB Lewy body, LBD Lewy body disease, LN Lewy neurite, PTM post-translational modification.