Table 1.
Baseline characteristics
| Overall (n = 1042) | No AKI (n = 761) | AKI (n = 267) | p | |
|---|---|---|---|---|
| Sex (male, n, %) | 710 (68.1) | 507 (66.6) | 193 (72.3) | 0.088 |
| Age (median, IQR) | 66.0 (56.0–75.0) | 65.0 (54.0–74.0) | 70.0 (59.0–78.0) | < 0.001 |
| Age group (n, %) | ||||
| < 40 | 62 (6.0) | 56 (7.4) | 6 (2.2) | < 0.001 |
| 40–60 | 297 (28.5) | 231 (30.4) | 65 (24.3) | |
| 60–80 | 558 (53.6) | 398 (52.3) | 152 (56.9) | |
| > 80 | 125 (12.0) | 76 (10.0) | 44 (16.5) | |
| SOFA Score (median, IQR) | 5.0 (4.0–7.0) | 4.0 (3.0–6.0) | 7.0 (4.0–9.0) | < 0.001 |
| SAPS 3 (median, IQR) | 53.0 (46.0–61.0) | 51.0 (46.0–60.0) | 58.0 (51.0–65.0) | < 0.001 |
| Comorbidities | ||||
| Hypertension (n, %) | 600 (57.6) | 406 (53.4) | 186 (69.7) | < 0.001 |
| Cardiovascular (n, %) | 387 (37.1) | 252 (33.1) | 131 (49.1) | < 0.001 |
| Obesity (BMI > 30) (n, %) | 322 (32.1) | 239 (32.7) | 82 (31.4) | 0.695 |
| Diabetes mellitus (n, %) | ||||
| No Diabetes | 729 (70.4) | 532 (70.4) | 185 (69.8) | 0.830 |
| DM Type 1 | 10 (1.0) | 8 (1.1) | 2 (0.8) | |
| DM Type 2 | 241 (23.3) | 174 (23.0) | 66 (24.9) | |
| Prediabetes | 55 (5.3) | 42 (5.6) | 12 (4.5) | |
| Chronic kidney disease (n, %) | 197 (18.9) | 110 (14.5) | 83 (31.1) | < 0.001 |
| Hepatic (n, %) | 88 (8.4) | 56 (7.4) | 31 (11.6) | 0.032 |
| Hematological malignancy (n, %) | 53 (5.1) | 33 (4.3) | 18 (6.7) | 0.119 |
| Non hematological malignancy (n, %) | 73 (7.0) | 51 (6.7) | 20 (7.5) | 0.666 |
| Immunosuppression (n, %) | 73 (7.0) | 47 (6.2) | 25 (9.4) | 0.079 |
| COPD (n, %) | 129 (12.4) | 89 (11.7) | 40 (15.0) | 0.163 |
| Asthma (n, %) | 45 (4.3) | 34 (4.5) | 11 (4.1) | 0.811 |
| Other respiratory (n, %) | 77 (7.4) | 50 (6.6) | 27 (10.1) | 0.059 |
| No known comorbidity (n, %) | 138 (13.8) | 122 (16.8) | 14 (5.4) | < 0.001 |
| Symptom onset to hospitalization (median, IQR) | 6 (4–9) | 6 (4–9) | 6 (3–9) | 0.704 |
| Symptom onset to ICU admission (median, IQR) | 8 (5–11) | 9 (6–11) | 8 (5–11) | 0.055 |
SOFA sequential organ failure assessment, SAPS 3 simplified acute physiology score 3, DM diabetes mellitus, COPD chronic obstructive pulmonary disease, ICU intensive care unit