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The extent of cutaneous disease in the mice depends on the injected amount of immune rabbit IgG. The extent of disease was scored as described in Methods and in Table 2. Means of individual clinical scores (n = 4) are shown before the first injection as well as 4, 8, and 12 days later. Significantly more extensive disease was induced in mice injected with 7.5 mg or 15 mg of immune IgG compared with mice treated with 3.75 mg of IgG.
