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Effects of hyperoxia and rIL-11 on epithelial cell A1 in vitro. MLE cells were incubated under normoxic or hyperoxic (95% O2) conditions (A and B) or in the presence or absence of rIL-11 (25 ng/ml) (C and D) for the noted periods of time, and the levels of mRNA encoding A1 (A and C) and the levels of A1 protein (B and D) were assessed by Northern and Western blot, respectively. The panels are representative of a minimum of 4 similar evaluations.
