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MRM chromatography of (A) blank equine plasma; (B) blank equine plasma spiked with furosemide, Rb1, Rb2, Rc, Rd (LLOQ), and digitoxin (IS, 500 ng/mL); and (C) equine plasma sample taken 15 min after 3 weeks of RG intake (600 mg/kg/day) and single injection of furosemide (0.5 mg/kg, IV). MRM, multiple reaction monitoring; LLOQ, lower limit of quantitation; IS, internal standard; RG, red ginseng.
