Table 4.
Estimated average annual percentage change in static perimetry measures based on log-transformed data
| Outcomes | Entire cohort (N=102) a | ------------ Preserved visual field cohort b ---------- | ||
|---|---|---|---|---|
| All (N=88) | False positives <15% (N=80) c | Outliers down-weighted (N=88) d | ||
| VTOT (%/year) | ||||
| Annual Change e | −8.3 | −8.8 | −8.3 | −7.3 |
| 95% CI | (−11.1, −5.5) | (−11.7, −5.7) | (−11.3, −5.2) | (−9.7, −4.8) |
| V30 (%/year) | ||||
| Annual Change e | −5.2 | −5.9 | −5.5 | −5.0 |
| 95% CI | (−7.4, −3.0) | (−7.9, −4.0) | (−7.4, −3.5) | (−6.8, −3.3) |
| VPERIPH (%/year) | ||||
| Annual Change e | −16.0 | −13.6 | −13.2 | −9.7 |
| 95% CI | (−22.0, −9.5) | (−19.2, −7.7) | (−19.1, −6.9) | (−13.7, −5.5) |
| Mean Sensitivity (%/year) | ||||
| Annual Change e | −5.1 | −5.4 | −5.1 | −4.9 |
| 95% CI | (−6.7, −3.5) | (−7.1, −3.7) | (−6.8, −3.4) | (−6.3, −3.5) |
a
Number of missing data: VTOT (4), VPERIPH (4), mean sensitivity (4)
b
Include participants with baseline VTOT >5 dB-sr
c
Tests with false positive rate <15%
d
Outliers were down-weighted using weighted mixed-effects model, weights were computed from robust regression modelling of estimate rate of decline from each participant
e
All P-values for testing the average annual change estimates against zero were <0.001