Figure 4.

HATCHet analysis of tumor heterogeneity for patient PCM034 identifies subclones with differential gains in chr8. Gains and losses for each chromosome are indicated as red or blue. The abundance of subclones is indicated with lighter colors showing less abundance and darker colors showing greater abundance. Four subclones were identified, with clone 1 containing a loss of chr8p and gain of chr8q being most prevalent in the LNM samples. Primary tumor foci were enriched in the normal subclone.