Table 3.
Any Positivity | >10% Positive Cells | |||||
---|---|---|---|---|---|---|
Sensitivity | Specificity | Sensitivity | Specificity | |||
SCLC n = 42 |
LCNEC n = 44 |
NSCLC n = 80 |
SCLC n = 42 |
LCNEC n = 44 |
NSCLC n = 80 |
|
Musashi-1 | 41 (98%) | 40 (91%) | 66 (83%) | 40 (95%) | 34 (77%) | 76 (95%) |
INSM1 | 40 (95%) | 30 (68%) | 70 (87%) | 36 (86%) | 20 (45%) | 80 (100%) |
Chromogranin-A | 35 (83%) | 23 (52%) | 77 (96%) | 28 (67%) | 15 (34%) | 80 (100%) |
Synaptophysin | 38 (90%) | 29 (66%) | 65 (81%) | 31 (73%) | 18 (41%) | 75 (94%) |
CD56 | 40 (95%) | 39 (89%) | 65 (81%) | 40 (95%) | 29 (66%) | 76 (95%) |
SCLC = small cell lung cancer, LCNEC = large cell neuroendocrine carcinoma, INSM1 = insulinoma-associated protein-1.