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. 2023 Nov 28;15(23):5623. doi: 10.3390/cancers15235623

Figure 1.

Figure 1

ABCC4 and ABCG2 involvement in CRC progression. ABCC4 and ABCG2 expression levels in “CRC” and noncancerous “Normal” colon tissue were calculated using data from GSE18105 (A,C) and GSE21510 (B,D) and visualised using Orange data mining 3.31.1 software. A normality test (Shapiro–Wilk) was performed, followed by the Mann–Whitney U test ** p < 0.005; *** p < 0.001; ABCC4 (E) and ABCG2 (F) impact on survival rate was analysed using TCGA data and visualised by the TIMER2.0 platform. The correlation of ABCC4 (G) and ABCG2 (H) wild-type (WT) and mutated variants was calculated using TCGA data and visualised by the TIMER2.0 platform. Wilcoxon test was performed, and the p-value is indicated in the figure.