Figure 5. Multivariate analysis of end-timepoint pathology.
A. Scatter plots of the optimal cell-type-based models of tau pathology at the end time points for each of the nine mouse tauopathy studies, along with their associated R2 values and the number of cell types chosen using the BIC. *: p < 0.01; **: p < 0.001; ***: p < 0.0001. B. Bar plot of the frequency with which cell types were included in the BIC-based linear models in A. Of the 42 cell types in the Yao, et al. dataset, 24 were selected at least once.