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[Preprint]. 2023 Nov 30:2023.02.04.527050. [Version 2] doi: 10.1101/2023.02.04.527050

Fig. 1. Nnat expression is a marker for late-stage beta cell differentiation during islet development.

Fig. 1.

(a-c) UMAP projection of scRNA-seq data from embryonic mouse islets (E12.5-E17.5), with cells labelled by their cellular state (a), pseudo-time (b), and corresponding Nnat expression (c). (d) Changes in the distribution of beta cell precursors from E12.5 to E17.5. (e, f) Violin plots showing the fluctuations in Ins1 (e) and Nnat (f) expression from E12.5 to adulthood in the beta cell development trajectory.