[Preprint]. 2023 Nov 28:2023.11.27.568812. [Version 1] doi: 10.1101/2023.11.27.568812

Table 4: Association between other biological variables and T cell subsets.

T cell subset		TCM		Naïve		TEMRA		TEM
Model		1	2	1	2	1	2	1	2
Aβ42/40 (p-value; R²)	CD4 ⁺	0.955; 0	0.785; 0.117	0.221; 0.02	0.306; 0.074	0.02; 0.072	0.032; 0.131	0.193; 0.023	0.221; 0.033
Aβ42/40 (p-value; R²)	CD8 ⁺	0.938; 0	0.91; 0.003	0.096; 0.037	0.175; 0.168	0.451; 0.008	0.681; 0.04	0.357; 0.012	0.343; 0.073
total tau (p-value; R²)	CD4 ⁺	0.036; 0.06	0.08; 0.153	0.023; 0.07	0.058; 0.108	0.73; 0.002	0.87; 0.066	0.145; 0.029	0.199; 0.035
total tau (p-value; R²)	CD8 ⁺	0.681; 0.002	0.672; 0.005	0.052; 0.051	0.207; 0.166	0.392; 0.01	0.711; 0.037	0.186; 0.024	0.261; 0.073
Nf-L (p-value; R²)	CD4 ⁺	0.619; 0.003	0.814; 0.086	0.05; 0.051	0.058; 0.088	0.07; 0.044	0.11; 0.086	0.037; 0.057	0.022; 0.078
Nf-L (p-value; R²)	CD8 ⁺	0.928; 0	0.908; 0.015	0.006; 0.098	0.03; 0.181	0.005; 0.102	0.021; 0.104	0.506; 0.006	0.423; 0.071
GFAP (p-value; R²)	CD4 ⁺	0.524; 0.006	0.295; 0.153	0.583; 0.005	0.804; 0.055	0.163; 0.029	0.384; 0.084	0.315; 0.015	0.301; 0.022
GFAP (p-value; R²)	CD8 ⁺	0.497; 0.007	0.582; 0.029	0.053; 0.055	0.149; 0.144	0.032; 0.068	0.086; 0.074	0.598; 0.004	0.536; 0.042

Model 1 is unadjusted. Model 2 includes age and gender. Sample size of analysis follows: Aβ42/Aβ40 (n=75), total tau (n=75), Nf-L (n=77), GFAP (n=69). Abbreviations: neurofilament light (Nf-L), glial fibrillary acidic protein (GFAP).