Figure A12.

The dynamics resulting from different choices of $\gamma$ and $dr$ can only be discriminated at small $R_{\mathrm{spheroid}}<150$ µm, where the transition between the linear and exponential regimes is observable. As an example, three choices of parameter sets with the same product $\gamma dr$ (same slope in the linear regime) are displayed for the FaDu cell line with 20 Gy irradiation (the solid line corresponds to parameters in Figure A6). The time $ln\left(2\right)/\gamma$ is varied in the fitting range used for the calibration of the RS model (20 h dashed line and 40 h dotted line).