Fig. 3 |. Differential gene expression and isoform usage in interferon stimulation and between brain regions finds novel genes and isoforms.

a, Schematic for generation of iPS-derived microglia and stimulation procedures. b, Differential gene expression finds multiple types of novel genes altered. c, Differential isoform usage finds novel isoforms altered. d, Schematic of the comparison between microglia from four brain regions. e, Differential expression finds novel genes mostly downregulated in microglia from the SVZ. f, Differential isoform usage finds novel isoforms downregulated compared to annotated isoforms in SVZ microglia. g, The AD-associated gene PICALM has region-specific differential isoform usage of 4 isoforms.