Table 1:
All isoforms discovered in microglia. NMD: nonsense-mediated decay; TSS: transcription start site. ATAC: assay for transposase-accessible chromatin.
| Isoform type | number | protein-coding | NMD-sensitive | TSS overlaps microglia ATAC-seq (Kosoy et al. 2022) |
|---|---|---|---|---|
| Full splice match | 92,557 | 63% | 12% | 57% |
| Incomplete splice match | 2,142 | 82% | 9.2% | 74% |
| Novel in catalog | 18,727 | 57% | 39% | 82% |
| Novel not in catalog | 11,607 | 43% | 45% | 70% |
| Fusion | 1,725 | 38% | 58% | 67% |
| Intergenic | 731 | 20% | 12% | 18% |
| Antisense | 621 | 16% | 12% | 10% |
| Genic | 326 | 25% | 38% | 61% |