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[Preprint]. 2023 Nov 30:2023.11.30.23299247. [Version 1] doi: 10.1101/2023.11.30.23299247

Figure 4. Role of BMI in the association of candidate causal proteins and MASLD.

Figure 4

A) Proteins as mediators in the causal association of BMI to MASLD. B) BMI as a mediator in the causal association of proteins to MASLD. C) Proteins directly associated with MASLD after adjusted for the causal effect of BMI by multivariable MR. D) Proteins not directly associated with MASLD after adjusted for the causal effect of BMI by multivariable MR. IVs: instrumental variables. Arrows indicate direction from MR analysis, or knowledge (i.e., IVs causes exposures, and BMI causes MASLD).