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[Preprint]. 2023 Dec 2:rs.3.rs-3627637. [Version 1] doi: 10.21203/rs.3.rs-3627637/v1

Figure 2.

Figure 2

Effects of moderate ethanol exposure from IKK-α/β to kB-a on LRP1 expression and NF-κB signaling in presymptomatic APP/PS1 mice. (A and B) Western blot quantification of LRP1/IKK-α/β/kB-α/NF-κB signaling. (C and D) Western blots results of LRP1/IKK-α/β/kB-α/NF-κB in the cortex and hippocampus of the presymptomatic APP/PS1 mice brains. β-Actin was used as a loading control. (A and C) Cortex, (B and D) Hippocampus. Data represent mean ± SEM; n = 5 per group. *P < 0.05 comparing each group. Two-tailed Mann-Whitney test. See Fig. S17 fora full Western blot and see Table S1 for full statistical information.