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[Preprint]. 2023 Dec 2:rs.3.rs-3627637. [Version 1] doi: 10.21203/rs.3.rs-3627637/v1

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Reduction of Aβ plaque formation in the cortex and hippocampus of ethanol-exposed presymptomatic APP/PS1 mice. Immunohistochemistry analysis shows the effects of MEE on Aβ plaque formation in the cortex and hippocampus of presymptomatic APP/PS1 mice. (A and B) Aβ plaques were visualized using Thioflavin S staining. (C and D) the number of plaques was significantly decreased in both cortex and hippocampus of ethanol-exposed presymptomatic APP/PS1 mice compared to air-exposed controls. Data represent mean ± SEM; n = 10 per group. *P < 0.05 comparing each group. Two-tailed Mann-Whitney test. See Table S1 for full statistical information.