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[Preprint]. 2023 Dec 2:rs.3.rs-3627637. [Version 1] doi: 10.21203/rs.3.rs-3627637/v1

Figure 5.

Figure 5

Reduction of Aβ levels in cortex and hippocampus of ethanol-exposed presymptomatic APP/PS1 mice. ELISA analysis shows the effects of chronic ethanol exposure on Aβ levels in the cortex and hippocampus of presymptomatic APP/PS1 mice. Quantification of amyloid Aβ1-40,42 levels using ELISA revealed a significant reduction in the cortex (A-C) and hippocampus (D-F) of ethanol-exposed presymptomatic APP/PS1 mice after 12 weeks of ethanol exposure compared to age-matched air-exposed presymptomatic APP/PS1 mice. Data represent mean ± SEM; n = 12 per group. *P < 0.05 comparing each group. Two-tailed Mann-Whitney test. See Table S1 for full statistical information.