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[Preprint]. 2023 Dec 2:rs.3.rs-3627637. [Version 1] doi: 10.21203/rs.3.rs-3627637/v1

Figure 7.

Figure 7

Effect of moderate ethanol exposure on cognitive performance in presymptomatic APP/PS1 mice. (A) Y-maze schematic diagram, (B) Y-maze test showing spontaneous alteration rate and (C) total arm entries for air-exposed and ethanol-exposed presymptomaticAPP/PS1 mice. (D) Novel Object Recognition (NOR) task schematic diagram, (E and F) NOR task demonstrating time spent exploring familiar and unfamiliar objects for both groups. (G) Morris water maze (MWM) schematic diagram, (H and I) MWM acquisitiontraining and probe test (J) reversal probe test. Data represent mean ± SEM; n= 12~28 per group. *P < 0.05 comparing each group. (B-C and E-F) Two-tailed Mann-Whitney test (H and J) Two-way ANOVA followed by Tukey’s multiple comparisons tests. See Table S1 for full statistical information.