Figure 2.

Comparison of experimental tumor growth curves with model prediction to define baseline values of model parameters. A) Experimental details for each experiment. B and C. Bullet points represent the experimental data and the continuous curves represent the model predictions. Day 0 is the initiation of the simulation, B) day 3, C) day 7 of the experiment. The vertical dashed black line represents the initiation of immunotherapy (anti-PD-L1). B) experimental data from Matson et al. ¹³ (B16 melanoma cells) and C) Gopalakrishnan et al. ¹⁴ (BP melanoma cells. In B and C, the control groups are germ-free mice and the rest of the groups received FMT from either a responder or a non-responder patient to immunotherapy.