Figure 2.

Behavioral and cognitive enhancement by CBD in Aβ_1–42-induced mice. Mice were injected with Aβ_1–42 (10 μg, 5 μL, i.c.v.), which was followed by CBD treatment (25 mg/kg, i.g.). (A) Experimental design schematic: (B) average swimming velocities across experimental groups; (C) traversed distances during the test by each group; (D) latency to locate the target platform during the final exploration trial; (E) temporal trend line depicting the duration mice took to reach the target platform during training; (F) swimming paths of mice targeting the hidden platform during the final exploration trial. Data are presented as mean ± SEM (n = 6). * p < 0.05 vs. sham + Veh group; ^# p < 0.05 vs. AD + Veh group, ns: not significant.