Table 4.

Conditions for the one-pot DMTMM reactions, including the pH, buffers, and temperature during the conjugation of nanogels with targeting ligand.

Reaction Scheme	pH at Activation	Buffer Used	Temperature
D1	pH 5.5	0.1 M MES buffer	4 °C
D2	pH 6.3
D3	pH 7.4	PBS