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Panels (a,c,e) present normal scanning electron microscopy images. The corresponding backscattered electron compositional (COMPO) images are presented in panels (b,d,f). In the COMPO images, the white areas are the locations in which the reflected electron emission rate is high, i.e., where atoms heavier than carbon, the main component of the cell, are present. Gold nanoparticles that are hidden by part of the cytoskeleton in (c,e) can be clearly observed in (d,f).
