PAKs	P21-activated kinases
PDA	Pancreatic ductal adenocarcinoma
TME	Tumour microenvironment
CSCs	Cancer stem cells
5-FU	5-fluorouracil
TKIs	Tyrosine kinase inhibitors
PFS	Progression-free survival
OS	Overall survival
MVD	Microvessel density
GTP	Guanosine triphosphate
MVI	Microvessel integrity
SEMA3A	Semaphorin 3A
SalB	Salvianolic acid B
HRG	Histidine-rich glycoprotein
RGS5	G-Protein Signalling 5
Cda	Cytidine deaminase
EMT	Epithelial–mesenchymal transition
VSMCs	Vascular smooth muscle cells
CSF2	Colony stimulating factor 2
HRG	Heregulin β1
HIF-1α	Hypoxia-inducible factor 1 alpha
JMJD6	Jumonji domain-containing protein 6
MMP9	Matrix metalloproteinases 9
CAFs	Cancer-associated fibroblasts
PSCs	Pancreatic stellate cells
KO	Knockout
KD	Knockdown
GBM ECs	Glioblastoma multiforme endothelial cells
IHC	Immunohistochemical