Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Nov 26;12(23):2711. doi: 10.3390/cells12232711

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Restorations of cholinergic ((A,C), n = 8–10/group) and dopaminergic ((B,D), n = 8–10/group) nervous systems following F3 or F3.ChAT cell transplantation. RT-PCR (A,B) and quantitative analyses (C,D) of the mRNA expression of cholinergic and dopaminergic components. Black: young animals (7 weeks old); red: aged animals; green: aged animals transplanted with F3 cells (1 × 10⁶ cells every month); blue: aged animals transplanted with F3.ChAT cells (1 × 10⁶ cells every month). ChAT: choline acetyltransferase. VAChT: vesicular acetylcholine transporter. ChT1: choline transporter 1, m1-AChR: muscarinic 1 acetylcholine receptor. nAChR: nicotinic acetylcholine receptor. AChE: acetylcholinesterase. GAPDH: glyceraldehyde-3-phosphate dehydrogenase. TH: tyrosine hydroxylase, VMAT2: vesicular monoamine transporter 2. DAT: dopamine transporter, DR: dopamine receptor. * Significantly different from young rats (p < 0.05). # Significantly different from aged rats (p < 0.05). + Significantly different from F3 treatment (p < 0.05).