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. 2023 Nov 24;24(23):16689. doi: 10.3390/ijms242316689

Figure 1.

Figure 1

Altered expressions of specific genes in GCs of follicles from PCOS women. Analysis of transcriptional change in genes associated with GC functions in GCs of PCOS and control women. Relative levels of (A) steroid receptors ESR1, PR, AR, ESR2v1, ESR2v2, ESR2v4, ESR2v5 and FSHR, (B) steroidogenic enzymes STAR, CYP11A1, HSD3B2 and CYP19A1 and (C) growth regulators BCL2, BAX, GREB1 and CCND1 mRNAs were determined via RT-qPCR analysis for each group. Transcript levels were normalized to GAPDH transcript abundance. Values are represented as means ± SEM (n = 6–14), measured in triplicate. Differences between groups were considered significant for p ≤ 0.05 * and p ≤ 0.01 ** via Mann–Whitney test. A.U., Arbitrary Units.